Is endothelium the key to solving a cardiovascular diseases problem, yes or no?

THE ARTICLE HIGHLIGHTS THE ROLE OF THE ENDOTHELIUM AS THE MOST IMPORTANT REGULATORY AND ENDOCRINE ORGAN THAT COORDINATES AND OPTIMIZES DIFFERENT METABOLIC AND PHYSIOLOGICAL PROCESSES IN THE CARDIOVASCULAR SYSTEM. THE HISTORY OF THE STUDY OF THE ENDOTHELIUM AND THE ROLE OF RUSSIAN SCIENTISTS ARE BRIEFLY DESCRIBED. THE MAIN FUNCTIONS OF THE VASCULAR ENDOTHELIUM IN NORMAL CONDITION AND IN PATHOLOGICAL PROCESSES, METHODS FOR DIAGNOSING ENDOTHELIAL DYSFUNCTION, AS WELL AS ROUTES AND METHODS OF ITS PHARMACOLOGICAL AND NON PHARMACOLOGICAL CORRECTION ARE INDICATED.