Clinical case of successful treatment of a patient with superior mesenteric artery syndrome

  • Sergey Yu. Puzanov Elizavetinskaya Hospital. 14, lit. A Vavilovykh str., Saint Petersburg 195257 Russian Federation
  • Anton V. Koshcheev Elizavetinskaya Hospital. 14, lit. A Vavilovykh str., Saint Petersburg 195257 Russian Federation
  • Sergey A. Podyezzhyh North-Western State Medical University named after I.I. Mechnikov. 41 Kirochnaya str., Saint Petersburg 191015 Russian Federation
  • Kyamalya N. Nadzhafova Elizavetinskaya Hospital. 14, lit. A Vavilovykh str., Saint Petersburg 195257 Russian Federation https://orcid.org/0000-0002-8419-0272
  • Maxim S. Ogay Almazov National Medical Research Centre. 2 Akkuratov str., Saint Petersburg 197341 Russian Federation
  • Ramin R. Nadzhafov Leningrad Regional Clinical Hospital. 37–39 Liteyny ave., Saint Petersburg 191014 Russian Federation
Keywords:
синдром Уилки синдром верхней брыжеечной артерии дуоденостаз операция Стронга Wilkie’s syndrome superior mesenteric artery syndrome duodenal obstruction Strong’s procedure

Abstract

Superior mesenteric artery syndrome (SMAS, Wilkie’s syndrome) is a rare, but potentially life-threatening cause of duodenal obstruction that results from a narrowing of the aortomesenteric angle and compression of the third portion of the duodenum between the aorta and the superior mesenteric artery. The condition is characterized by non-specific clinical symptoms, which often lead to misdiagnosis and delayed treatment. This article presents a case of a 37-year-old woman with a severe course of SMAS who had been under long-term observation for suspected gastrointestinal pathology. The diagnosis was confirmed via CT angiography. Following a phase of nutritional and metabolic correction, the patient underwent Strong’s procedure with subtotal gastrectomy and Roux-en-Y reconstruction. Surgical treatment led to a sustained clinical and metabolic remission and recovery of the patient’s nutritional status. This case highlights the importance of early diagnosis of rare causes of duodenal stasis in patients with persistent weight loss and postprandial vomiting.

 

References

Apostu R.C., Chira L., Colcear D., Lebovici A., Na­gy G., Scurtu R.R., Drasovean R. Wilkie’s syndrome as a cause of anxiety-depressive disorder: A case report and review of literature. World J Clin Cases. 2022;10(5):1654–1666.

Lundell L., Thulin A. Wilkie’s syndrome — a rarity? British Journal of Surgery. 1980;67(8):604–606.

WILKIE D. P. D.: Chronic duodenal ileus. Br. J. Surg. 1921;9:204–14.

WILKIE D. P. D.: Chronic duodenal ileus. Am. J. Med. Sci. 1927;173:643–9.

Van Horne N., Jackson J.P. Superior mesenteric artery syndrome. In: StatPearls. Treasure Island: StatPearls Publishing; 2021.

Oka A., Awoniyi M., Hasegawa N., Yoshida Y., Tobita H., Ishimura N., Ishihara S. Superior mesenteric artery syndrome: Diagnosis and management. World J Clin Cases. 2023;11(15):3369–3384.

Johnson B.M., Paladugu G. Superior Mesenteric Artery Syndrome Secondary to Anorexia Nervosa and Methamphetamine Use. Cureus. 2019;11(11):e6121.

Cervantes Perez E., Martínez-Soto Holguin M.C., Diaz Juárez J.P., Reyes Ramrez ALDC. Síndrome de Wilkie secundario a hipertiroidismo exógeno en una paciente con hipotiroidismo primario autoinmune: reporte de un caso y revisión de la literatura [Wilkie’s syndrome caused by exogenous hyperthyroidism in a patient with primary autoimmune hypothyroidism: a case report and literature review]. Rev Gastroenterol Peru. 2020;40(3):274–277.

Farina R., Foti P.V., Cocuzza G., Costanzo V., Costanzo G., Conti A., Torcitto A., Pennisi M. Wilkie’s syndrome. J. Ultrasound. 2017;20:339–342.

Unal B., Aktaş A., Kemal G., Bilgili Y., Güliter S., Daphan C., Aydinuraz K. Superior mesenteric artery syndrome: CT and ultrasonography findings. Diagn Interv Radiol. 2005;11:90–95.

Ren P.L.J., Gupta A. Adolescent with Superior Mesente­ric Artery Syndrome. J. Radiol. Case Rep. 2020;14:14–23.

Ciortescu I., Nemteanu R., Hincu C., Gheorghe L., Plesa A. An Underrated Diagnosis of Superior Me­senteric Artery Syndrome: A Case Report. Diagnostics (Basel). 2022;12(9):2159.