История изучения ювенильной фибромиалгии: к 40-летию первого описания. Часть II. Клиническая картина. Дифференциальная диагностика. Коморбидность
Аннотация
Muhammad B. Yunus и Alfonse T. Masi в феврале 1985 года впервые описали 33 случая ювенильной первичной фибромиалгии (ФМ) и предложили ее диагностические критерии, однако и 40 лет спустя практические врачи зачастую испытывают затруднения при ее диагностике и лечении. Это во многом связано с недостаточной информированностью детских врачей о данной проблеме, так как в доступной зарубежной литературе информации о ювенильной фибромиалгии (ЮФМ) на несколько порядков меньше, чем о ФМ у взрослых пациентов, а в русскоязычных научных статьях вопросы ЮФМ практически не обсуждаются. Большинство опубликованных ранее обзоров литературы, посвященной ЮФМ, как правило, приводят информацию не только непосредственно о ней, но и, в большей степени, о ФМ у взрослых, что не вполне корректно, так как существует целый ряд уникальных особенностей ЮФМ и ее отличий от ФМ у взрослых. Цель настоящего обзора — обобщить оригинальные исследования ЮФМ, избегая ссылок на исследования с участием только взрослых пациентов. В части II статьи приведены данные о клинической картине, дифференциальной диагностике и коморбидности ЮФМ.
Библиографические ссылки
Yunus M.B., Masi A.T. Juvenile primary fibromyalgia syndrome. A clinical study of thirty-three patients and matched normal controls. Arthritis Rheum. 1985;28(2):138–45. DOI: 10.1002/art.1780280205.
Siegel D.M., Janeway D., Baum J. Fibromyalgia syndrome in children and adolescents: clinical features at presentation and status at follow-up. Pediatrics. 1998;101(3 Pt 1):377–82. DOI: 10.1542/peds.101.3.377.
Rusy L.M., Harvey S.A., Beste D.J. Pediatric fibromyalgia and dizziness: evaluation of vestibular function. J Dev Behav Pediatr. 1999;20(4):211–5. DOI: 10.1097/00004703-199908000-00002.
Gedalia A., García C.O., Molina J.F. et al. Fibromyalgia syndrome: experience in a pediatric rheumatology clinic. Clin Exp Rheumatol. 2000;18(3):415–9.
Cheng X.F., Tan J., Tan K.L. Clinical analysis of six cases with juvenile primary fibromyalgia syndrome. Zhonghua Er Ke Za Zhi. 2005;43(11):863–5.
Eraso R.M., Bradford N.J., Fontenot C.N. et al. Fibromyalgia syndrome in young children: onset at age 10 years and younger. Clin Exp Rheumatol. 2007;25(4):639–44.
Alfvén G. Recurrent pain, stress, tender points and fibromyalgia in childhood: an exploratory descriptive clinical study. Acta Paediatr. 2012;101(3):283–91. DOI: 10.1111/j.1651-2227.2011.02491.x.
Itoh Y., Shigemori T., Igarashi T., Fukunaga Y. Fibromyalgia and chronic fatigue syndrome in children. Pediatr Int. 2012;54(2):266–71. DOI: 10.1111/j.1442-200X.2011.03514.x.
Durmaz Y., Alayli G., Canbaz S. et al. Prevalence of juvenile fibromyalgia syndrome in an urban population of Turkish adolescents: impact on depressive symptoms, quality of life and school performance. Chin Med J (Engl). 2013;126(19):3705–11.
Kovacic K., Chelimsky T.C., Sood M.R. et al. Joint hypermobility: a common association with complex functional gastrointestinal disorders. J Pediatr. 2014;165(5):973–8. DOI: 10.1016/j.jpeds.2014.07.021.
Chelimsky G., Kovacic K, Nugent M. et al. Comorbid Conditions Do Not Differ in Children and Young Adults with Functional Disorders with or without Postural Tachycardia Syndrome. J Pediatr. 2015;167(1):120–4. DOI: 10.1016/j.jpeds.2015.03.039.
Otu-Nyarko C.G., Gedalia A., Karpinski A.C. et al. Disability in Children and Adolescents With Irritable Bowel Syndrome and/or Fibromyalgia. J Pediatr Gastroenterol Nutr. 2015;61(5):558–60. DOI: 10.1097/MPG.0000000000000886.
Sil S., Thomas S., DiCesare C. et al. Preliminary evidence of altered biomechanics in adolescents with juvenile fibromyalgia. Arthritis Care Res (Hoboken). 2015;67(1):102–11. DOI: 10.1002/acr.22450.
Maia M.M., Gualano B., Sá-Pinto A.L. et al. Juvenile fibromyalgia syndrome: Blunted heart rate response and cardiac autonomic dysfunction at diagnosis. Semin Arthritis Rheum. 2016;46(3):338–343. DOI: 10.1016/j.semarthrit.2016.07.002.
Cunningham N.R., Kashikar-Zuck S., Mara C. et al. Development and validation of the self-reported PROMIS pediatric pain behavior item bank and short form scale. Pain. 2017;158(7):1323–1331. DOI: 10.1097/j.pain.0000000000000914.
Zwir L., Fraga M., Sanches M. et al. A case-control study about bite force, symptoms and signs of temporomandibular disorders in patients with idiopathic musculoskeletal pain syndromes. Adv Rheumatol. 2018;58(1):7. DOI: 10.1186/s42358-018-0006-z.
Weiss J.E., Schikler K.N., Boneparth A.D. et al. Demographic, clinical, and treatment characteristics of the juvenile primary fibromyalgia syndrome cohort enrolled in the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry. Pediatr Rheumatol Online J. 2019;17(1):51. DOI: 10.1186/s12969-019-0356-z.
Connelly M., Weiss J.E. For the CARRA Registry Investigators. Pain, functional disability, and their Association in Juvenile Fibromyalgia Compared to other pediatric rheumatic diseases. Pediatr Rheumatol Online J. 2019;17(1):72. DOI: 10.1186/s12969-019-0375-9.
Sherry D.D., Sonagra M., Gmuca S. The spectrum of pediatric amplified musculoskeletal pain syndrome. Pediatr Rheumatol Online J. 2020;18(1):77. DOI: 10.1186/s12969-020-00473-2.
Dell’Erba S., Melissano P., Zegretti A. et al. Psychological characteristics of juvenile fibromyalgia syndrome. Pediatr Int. 2023;65(1):e15449. DOI: 10.1111/ped.15449.
Maddali Bongi S., Vitali Rosati G., Bonaccorsi G., Lorini C. Prevalence and Contextual Factors of Juvenile Fibromyalgia in a Population-Based Italian Sample of Children and Adolescents. Biomedicines. 2023;11(6):1583. DOI: 10.3390/biomedicines11061583.
Lynch-Jordan A.M., Connelly M., Guite J.W. et al. Clinical Characterization of Juvenile Fibromyalgia in a Multicenter Cohort of Adolescents Enrolled in a Randomized Clinical Trial. Arthritis Care Res (Hoboken). 2023;75(8):1795–1803. DOI: 10.1002/acr.25077.
Gibler R.C., Peugh J.L., Pfeiffer M. et al. Associations between patient-reported functional disability and measures of physical ability in juvenile fibromyalgia. Pain. 2024;165(3):589–595. DOI: 10.1097/j.pain.0000000000003040.
Kashikar-Zuck S., Thomas S., Bonnette S. et al. Comparison of Pain Characteristics, Strength, and Movement Patterns in Adolescents With Juvenile Fibromyalgia and High Versus Low Fear of Movement. J Pain. 2024:104586. DOI: 10.1016/j.jpain.2024.104586.
Malattia C., Chiappe G., Capurro C. et al. High prevalence of orofacial pain in juvenile fibromyalgia as detected by a novel tool specifically devised for children and adolescents. Clin Exp Rheumatol. 2024;42(6):1272–1279. DOI: 10.55563/clinexprheumatol/rnlerg.
Gupta A., Schikler K. Prevalence of tinnitus in juvenile fibromyalgia patients visiting a pediatric rheumatology clinic. Int J Pediatr Otorhinolaryngol. 2024;176:111837. DOI: 10.1016/j.ijporl.2023.111837.
Keenan G.F., Ostrov B.E., Goldsmith D.P., Athreya B.H. Rheumatic symptoms associated with hypothyroidism in children. J Pediatr. 1993;123(4):586–8. DOI: 10.1016/s0022-3476(05)80957-6.
McLeod J.D. Juvenile fibromyalgia syndrome and improved recognition by pediatric primary care providers. J Pediatr Health Care. 2014;28(2):e9–18. DOI: 10.1016/j.pedhc.2013.05.008.
Bakkaloğlu S.A., Muzaç S., Akpek S. et al. Polyarteritis nodosa in a case of familial Mediterranean fever. Pediatr Nephrol. 2004;19(5):536–8. DOI: 10.1007/s00467-003-1390-z.
Alayli G., Durmus D., Ozkaya O. et al. Frequency of juvenile fibromyalgia syndrome in children with familial Mediterranean fever: effects on depression and quality of life. Clin Exp Rheumatol. 2011;29 (6 Suppl 69):S127–32.
Taubman B., Mamula P., Sherry D.D. Prevalence of asymptomatic celiac disease in children with fibromyalgia: a pilot study. Pediatr Rheumatol Online J. 2011;9:11. DOI: 10.1186/1546-0096-9-11.
Barfield E., Solomon A. An adolescent female with chronic musculoskeletal pain. Clin Pediatr (Phila). 2013;52(7):684–6. DOI: 10.1177/0009922813488656.
Сантимов А.В. Жданова М.В. Новик Г.А. Диета при фибромиалгии. Университетский терапевтический вестник. 2024;6(4):100–122. DOI: 10.56871/UTJ.2024.13.47.009. Santimov A.V., Zhdanova M.V., Novik G.A. Diet for fibromyalgia. University Therapeutic Journal. 2024;6(4):100–122. (In Russian). DOI: 10.56871/UTJ.2024.13.47.009.
Сантимов А.В. Роль диеты в развитии и лечении ревматических заболеваний у детей. Children’s Medicine of the North-West. 2024;12(4):101–119. DOI: 10.56871/CmN-W.2024.65.19.007. Santimov A.V. The role of diet in the development and treatment of rheumatic diseases in children. Children’s Medicine of the North-West. 2024;12(4):101–119. (In Russian). DOI: 10.56871/CmN-W.2024.65.19.007.
Медик В.А., Токмачев М.С. Руководство по статистике здоровья и здравоохранения. М.: Медицина; 2006. EDN: QLMGUT. Medik V.A., Tokmachev M.S. Guide to Health and Healthcare statistics. Moscow: Medicine; 2006. (In Russian). EDN: QLMGUT.
Сантимов А.В., Гречаный С.В., Новик Г.А. Вторичная фибромиалгия при остеоартрите и гипермобильности суставов у детей. Children’s Medicine of the North-West. 2025;13(1):129–142. DOI: 10.56871/CmN-W.2025.30.28.010. Santimov A.V., Grechany S.V., Novik G.A. Secondary fibromyalgia in osteoarthritis and joint hypermobility in children. Children’s Medicine of the North-West. 2025;13(1):129–142. (In Russian). DOI: 10.56871/CmN-W.2025.30.28.010.
Ramprakash S., Fishman D. Juvenile fibromyalgia in an adolescent patient with sickle cell disease presenting with chronic pain. BMJ Case Rep. 2015;2015:bcr2015211850. DOI: 10.1136/bcr-2015-211850.
Torrente-Segarra V., Salman Monte T.C., Rúa-Figueroa I. et al. Juvenile- and adult-onset systemic lupus erythematosus: a comparative study in a large cohort from the Spanish Society of Rheumatology Lupus Registry (RELESSER). Clin Exp Rheumatol. 2017;35(6):1047–1055.
Tesher M.S., Graham T.B., Ting T. et al. Juvenile Fibromyalgia in Patients With Juvenile Idiopathic Arthritis: Utility of the Pain and Symptom Assessment Tool. Arthritis Care Res (Hoboken). 2022;74(12):2085–2090. DOI: 10.1002/acr.24739.
Özomay Baykal G., Kurtuluş D., Ata S., Sözeri B. Prevalence and characteristics of juvenile fibromyalgia syndrome in pediatric rheumatic diseases: A comparative study. Arch Rheumatol. 2024;39(3):384–392.
