ORAL CAVITY CHANGES WITH PROTON PUMP INHIBITORS

Introduction. In modern medicine, taking proton pump inhibitors (PPIs) is one of the most effective methods for treating gastroesophageal reflux disease (GERD). In recent years, an opinion has emerged that PPIs negatively affect the gastrointestinal microbiome, as well as the salivary microbiota. The effect of PPIs in patients with GERD on the oral cavity and the development of dental diseases requires further study. The aim of the work is to establish the effect of proton pump inhibitors on the oral cavity and dental health of patients depending on the duration of drug use.

Conclusions. During our study, we were able to prove that GERD before and during PPI treatment remains an aggravating factor in the development of dental diseases. Treatment of such patients should be comprehensive by gastroenterologists and dentists.