THE ANALYSIS OF THE FACTORS THAT MAY LEAD TO DEVELOPMENT OF ANXIETY AND DEPRESSION DISORDERS IN PATIENTS WITH METABOLIC SYNDROME
Abstract
The high prevalence of obesity and insulin resistance, which are the pathogenetic basis for the formation of the metabolic syndrome (MtS), the relationship between metabolic and anxiety - depressive disorders established in the course of a galaxy of studies dictate the need for a detailed study of this problem. Purpose of the study. To identify probable factors that increase the chance of developing psycho - emotional disorders in the form of anxiety and depression in patients with MtS, and to determine the vector for further study of the indicated problem. Material and methods. The data of 241 patients with metabolic syndrome, whose average age was 53,1±12,5 years, studied. The presence and severity of anxiety - depressive disorder was determined using the Anxiety and Depression Scale (HADS). Potential factors influencing the development of psycho - emotional disorders of the anxiety - depressive spectrum selected based on the results of interpreting the data of a specially designed questionnaire. Eating behavior and quality of life were assessed using the Eating Behavior Questionnaire (DEBQ), the Eating Attitudes Test (EAT-26), and the SF-36 questionnaire. Results. Modifiable factors identified that potentially increase the chances of developing anxiety and depression in patients with MS: along with female gender, age, and unfavorable socioeconomic aspects of life, type 2 diabetes mellitus and MtS-associated gastrointestinal diseases make a certain contribution. The results obtained in the future will contribute to the choice of optimal tactics for primary and secondary prevention of the development of psychosocial personality disorders in these patients; however, to obtain reliable results, a logistic regression analysis of the studied cohort with a large number of observations is required.
