ORAL MESALAZINE DRUGS FOR ULCERATIVE COLITIS: CURRENT CLINICAL PRACTICE

  • Yury P Uspenskiy Saint-Petersburg State Pediatric Medical University; Pavlov First Saint-Petersburg State Medical University 194100, Saint-Petersburg; 197022, Saint-Petersburg
  • Sergey V Ivanov Saint-Petersburg State Pediatric Medical University; Pavlov First Saint-Petersburg State Medical University 194100, Saint-Petersburg; 197022, Saint-Petersburg
  • Yulia A Fominykh Saint-Petersburg State Pediatric Medical University; Pavlov First Saint-Petersburg State Medical University 194100, Saint-Petersburg; 197022, Saint-Petersburg
  • Andrey M Sarana Saint-Petersburg State University 199034, Saint-Petersburg
  • Ruslan O Dreval Non-profit organization “Center for Social Economy” 119421, Moscow
Keywords:
язвенный колит 5-аминосалициловая кислота месалазин ulcerative colitis 5-aminosalicylic acid mesalazine

Abstract

The article represents the role of oral 5-aminosalicylic acid(5-ASA) drugs in the structure of the basic therapy of ulcerative colitis according to current clinical guidelines. The results of current epidemiological studies reflecting the features of the use of oral preparations 5-ASA in clinical practice in the context of the length of colon lesions are presented, a high frequency of use of monotherapy with oral 5-ASA preparations were noted. The spectrum of currently used oral preparations 5-ASA and their features that determine the flow of the active substance into the mucous membrane of the affected areas of the colon are presented.

Author Biographies

Yury P Uspenskiy, Saint-Petersburg State Pediatric Medical University; Pavlov First Saint-Petersburg State Medical University 194100, Saint-Petersburg; 197022, Saint-Petersburg
Litovskaya str., 2; Leo Tolstoy str., 6-8
Sergey V Ivanov, Saint-Petersburg State Pediatric Medical University; Pavlov First Saint-Petersburg State Medical University 194100, Saint-Petersburg; 197022, Saint-Petersburg
Litovskaya str., 2; Leo Tolstoy str., 6-8; PhD, Associate Professor of Department of internal diseases of Dentistry faculty
Yulia A Fominykh, Saint-Petersburg State Pediatric Medical University; Pavlov First Saint-Petersburg State Medical University 194100, Saint-Petersburg; 197022, Saint-Petersburg
Litovskaya str., 2; Leo Tolstoy str., 6-8
Andrey M Sarana, Saint-Petersburg State University 199034, Saint-Petersburg
Universitetskaya Embankment, 7-9
Ruslan O Dreval, Non-profit organization “Center for Social Economy” 119421, Moscow
Leninsky pr., 111, Build 1