The impact of statins on the state of the endothelium
Keywords:
статины
эндотелиальная дисфункция
гиполипидемические эффекты статинов
плейотропные эффекты статинов
statins
endothelial dysfunction
hypolipidemic effects of statins
pleiotropic effects of statins
Abstract
Statins are being actively introduced into clinical use, since they represent an opportunity to reduce the risk of development and progression of cardiovascular diseases. Mechanisms of action of statins, their hypolipidemic and pleiotropic effects, routes of exposure to the functional state of the endothelium have been discussed. The use of statins in combination therapy of cardiovascular diseases is able to slow down the progression of cardiovascular diseases.



